Oral Chelation Review

Oral Chelation—The Strongest Drug Free Treatment for Your Heart, Arteries, Memory, and More!

If you are currently taking an oral chelation supplement, you’re already aware that this surprisingly powerful, but safe and inexpensive treatment can erase everything from chest pain and high blood pressure…to the symptoms that lead to heart attack and stroke. What you may not know is that the latest research indicates that your body requires a minimum dose to achieve and maintain significant changes in your health and well-being—a dose which the majority of oral chelation treatments available today fail to supply. Another often-missed truth is that there is not just one, but a number of very effective natural chelating agents that can work together to greatly enhance the protective and preventive benefits of this health-enhancing treatment. Please take a moment to read this important information; you may be able to provide even greater support for your heart health, energy, and longevity.

Every year, nearly six million Americans end up in the hospital, suffering from a disease that is largely preventable, reversible—even curable. I’m referring, of course, to cardiovascular disease (CVD.) CVD includes congestive heart failure—the single most frequent cause of hospitalization for people aged 65 years or older; heart disease (the leading cause of premature, permanent disability among working adults), and stroke (currently the cause of disability in over one million Americans.) In fact, CVD is the nation’s leading killer for both men and women over age 50, among all racial and ethnic groups, claiming the lives of over 800,000 Americans every year. Perhaps even more startling: nearly one in two American adults—about 128.5 million—lives with some form of CVD. But it doesn’t have to be that way. You don’t have to be a victim of CVD. Nor do you have to submit to dangerous, expensive surgery or heart drugs. If you or a loved one suffers from any form of CVD, here is the simple— but too often overlooked—truth about how this prevalent killer operates. What the public at large tends not to realize—and what your doctor has likely failed to explain to you—is that the primary precursor to heart disease, atherosclerosis (hardened arteries) is not a localized injury. It’s a systemic condition. In other words, atherosclerosis is present not only in the coronary arteries, but also in the brain, lungs, kidneys, and legs. What’s more, the blockages that lead to atherosclerosis can occur not only in the larger vessels—the vessels that can be seen and manipulated by surgeons and cardiologists—but in the smaller blood vessels as well. It is in these smaller blood vessels, the capillaries, that the oxygen exchange to the tissues takes place. You can protect that critical lifeline of oxygen that feeds and sustains the organs and tissues throughout your body—including your heart. There exists today a treatment that removes plaque and restores blood flow throughout the entire arterial system, treating the micro as well as the macro vessels. It’s called EDTA chelation, available via intravenous and oral supplementation. You should consider chelation therapy—safe, inexpensive, and proven effective—if you have a family history of CVD or existing CVD. You should also consider chelation if you simply want to do everything within your power to prevent CVD … and the potentially disastrous effects of the conventional medical treatments for this deadly disease.

If you are currently taking an oral chelation supplement, you’re already aware that this surprisingly powerful, but safe and inexpensive treatment can erase everything from chest pain and high blood pressure…to the symptoms that lead to heart attack and stroke. What you may not know is that the latest research indicates that your body requires a minimum dose to achieve and maintain significant changes in your health and well-being—a dose which the majority of oral chelation treatments available today fail to supply. Another often-missed truth is that there is not just one, but a number of very effective natural chelating agents that can work together to greatly enhance the protective and preventive benefits of this health-enhancing treatment. Please take a moment to read this important information below; you may be able to provide even greater support for your heart health, energy, and longevity.

Treating your heart the conventional way—with plastic balloons and cabbages …

Traditional medicine approaches heart disease primarily in one of two ways. The first is to ream out clogged arteries or flatten deposits in the vessels with angioplasty. This procedure does have some risk for heart attack or making the blockage even worse.{ref2} Many of the blockages return to their original severity within a year.

The second way is to cut away the clogged section or sections of the artery and replace it with a new section or sections of arteries grafted from other places in the body. This procedure is called a coronary artery bypass graft, or CABG… known in the medical profession as “cabbage.” An appropriate nickname, perhaps, as it’s also a nickname for money… and CABG, the most frequently performed surgery in the United States, costs up to $50,000 per procedure.

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If your doctor has recommended CABG to you or a loved one, you should know that the average mortality for CABG surgery is 4% to 10%.{ref3}{ref4} And a common “side effect” after the procedure is cerebral dysfunction—memory loss and mental decline.{ref5}

But it saves lives…right? Not according to the New England Journal of Medicine. According to a pivotal study published in this prestigious medical journal, CABG, compared with less invasive and risky medical therapy, “appears neither to prolong life nor to prevent myocardial infarction [heart attack] in patients who have mild angina [chest pain] or who are asymptomatic [suffer no pain] after infarction in the five-year period after coronary angiography.” {ref6}

The failure of standard medical treatments to heal heart patients doesn’t really come as a surprise. Fact is, any treatment that fails to support the circulation throughout your entire body is likely to fail you—and your health—in the long run. But cardiovascular surgery and other conventional heart treatments are enormously—almost unimaginably—profitable. CABG alone generates as much as $18.4 billion per year. {ref7} Drugs for reducing cholesterol, lowering high blood pressure, and normalizing heart rhythm brings the pharmaceutical industry hundreds of millions of dollars each year.

Meanwhile, chelation therapy is a potent, safe, inexpensive and virtually risk-free heart and circulation treatment … and recent research suggests it may in fact, be the single most powerful treatment for CVD.

A godsend for victims of heavy metal poisoning … and those who want to prevent and reverse atherosclerosis

In the days after World War II, men who worked in battery factories or painted ships with lead-based paint began coming down with lead poisoning from their high exposure in these jobs. A safe, harmless chemical called EDTA was found to be extremely effective for removing the lead from the men’s bodies—an effective cure for lead poisoning. But something else happened to many of the men who were treated with EDTA: they enjoyed an apparent reduction in symptoms of heart disease.

How does it work? Let’s start with a few basics.

A chelate is a chemical compound in which the central atom (usually a metal ion) is attached to neighboring atoms by at least two bonds in such a way as to form a ring structure. Chelating is the process in which the metal ion reacts with another molecule to form the chelate. EDTA (ethylenediaminetetraacetic acid) is an amino acid. It was synthesized in Germany in 1935 and first patented in the U.S. in 1941. Chelation therapy itself can be understood simply as the removal of calcium deposits (from your arteries, where you don’t want them) and other harmful minerals that promote blood clotting and atherosclerosis. Since these harmful deposits are also known to cause excessive free radical production, EDTA chelation also functions as a powerful free radical buster … protecting cell membranes, DNA, enzyme systems, and lipoproteins from the destructive effects of these ravenous molecules. Some experts believe that the primary benefits of chelation are due to its free radical-fighting effects.{ref8} And perhaps one of the most compelling, but often overlooked, explanations for chelation’s anti-aging, energizing effects is that EDTA “resuscitates” your cells’ mitochondria. Mitochondria are the “power plants” of every cell in the body—the site in which the energy-producing ATP is generated. Without ATP, life can not exist.{ref9} Loss of mitochondrial function has long been considered to be one of the primary causes of the aging process.{ref10}

But don’t look to the mainstream community for the truth about this powerful, life-saving therapy

The American Heart Association (AHA) recognizes chelation therapy as a treatment for heavy metal poisoning. The AHA admits that EDTA, injected into the blood, will bind the metals and allow them to be removed from the body in the urine. In fact, EDTA is the standard FDA approved treatment for lead, mercury, aluminum, and cadmium poisoning.

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But neither the FDA nor the AMA acknowledges that chelation appears to be one of the most powerful—yet least expensive … and safest—treatments for heart disease in existence. The bottom line: chelation therapy, which costs only $2,000 to $4,000 per course—represents a significant threat to one of the largest income streams for conventional practitioners. Clearly, if EDTA chelation had a large pharmaceutical company advocating its use … it would, at the very least, be integrated into the standard, AMA-approved treatment for heart disease. But the patent for EDTA ran out nearly 30 years ago. No patent means no profits. And if the medical industry can’t profit from chelation … this safe, inexpensive, powerful treatment … it may as well not exist.

50+ years of proof: Chelation could save hundreds of thousands of lives … every year

From its earliest clinical tests, chelation therapy has consistently demonstrated a remarkable ability to cleanse the system of metals and other deposits that lead to so-called age-related disease. In 1955, research conducted at the Providence Hospital in Detroit, Michigan, found that EDTA dissolves “metastatic calcium”—i.e., calcium that has been deposited where it is not wanted. Namely, arteries, joints, kidneys, and even the bones of the inner ear. In other words, chelation therapy appeared to be a powerful antidote to—and preventative against—atherosclerosis, arthritis, kidney stones, and otosclerosis (hearing loss related to the calcification of the bones in the ear).{ref11}

Nineteen out of 20 heart patients enjoyed measurable improvement in energy and activity level

The first systematic study of EDTA in people with atherosclerosis was published in 1956. Twenty patients with confirmed heart disease were given a series of 30 EDTA treatments intravenously. Nineteen of the patients experienced improvement, as measured by an increase in physical activity.{ref12}

Chest pain reduced … energy and work capacity increased

In another study conducted four years later, a similar group found that three months of EDTA infusions caused decreases in the severity and frequency of anginal episodes, reduced use of nitroglycerin (a common anti-angina drug), increased work capacity and improved ECG (electrocardiogram) results.{ref13}

Thousands upon thousands of patients have already experienced the powerful benefits of chelation treatment

Since these early studies, hundreds of papers have been published on the favorable effects of chelation therapy in a variety of chronic diseases. There have even been two massive “meta-analyses” of published and unpublished studies evaluating the results of over 24,000 chelation patients.{ref14} The results: 88 percent of the patients demonstrated clinical improvement.

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One of the studies included 92 patients who were referred for surgical intervention. At the end of the study, only 10 required surgery either during or after their chelation therapy.{ref15} In another study of 2,870 patients with various degrees of degenerative diseases, especially vascular disease, almost 90% of the patients showed excellent improvement.{ref16} In one small, controlled crossover study of patients with peripheral vascular disease, results showed significant improvements in walking distance and ankle/brachial blood flow.{ref17}

And when, in one study, 65 patients on the waiting list for CABG surgery (for a mean of 6 months) were treated with EDTA chelation therapy … the symptoms in 89% improved so much they were able to cancel their surgery. In the same study, of 27 patients recommended for limb amputation due to poor peripheral circulation, EDTA chelation resulted in saving 24 limbs.{ref18}

Make your arteries “younger”

Another tremendous source of information about chelation is a gentleman known as the “father” of the modern chelation movement, as well a world-renowned expert on nutrition, mineral metabolism, and alternative and preventative therapies, Garry Gordon, MD, DO. Dr. Gordon wrote the original protocol for the safe and effective use of EDTA. In an interview Dr. Gordon explained some of the extraordinary results he has accumulated in his use and study of EDTA Chelation, including the following:

Common anti-clotting therapies like aspirin and coumadin are effective against only about one-third of excessive platelet aggregation and coagulation (“sticky” blood and plaque formation. What’s worse, aspirin) has a well-known corrosive effect on the membrane of the stomach, causing a micro-hemorrhage right where the pill hits the stomach. EDTA, on the other hand, appears to reduce all harmful clotting mechanisms. According to Dr. Gordon, “In a proper combination with other natural anti-clotting substances, oral EDTA is a safe and effective alternative. I’ve known people who had such poor peripheral circulation that their feet were black bordering on gangrene. After oral EDTA, their black feet became pink again.”

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EDTA actually stimulates bone growth through a complex action of the parathyroid gland. Even though it is removing calcium from plaque in blood vessels, it has the ability to make bones stronger. Dr. Gordon believes that chelation can significantly reduce the incidence of osteoporosis. “The more chelation we give people, the less osteoporosis they have and the less age-related calcium accumulation there is in their blood vessels. The average 80-year-old man … shows 140 times more calcium than he had at age 10. This means you’re gradually turning to stone in all your arteries. We can document that calcium accumulation in the artery is totally reversible by enough chelation.”

“I use IV treatment to get people’s arteries younger,” says Dr. Gordon, “and to increase blood flow in their arteries.” Remarkably, while conventionally trained cardiologists consider the diagnosis of congestive heart failure to be virtually a death sentence—over 60 percent of their patients are dead within the first year—Dr. Gordon hasn’t lost one patient with congestive failure in 10 years.

But chelation therapy is far more than just a powerful heart and circulation treatment. As a result of its complex of health-enhancing, detoxifying benefits … chelation therapy helps to correct, reverse, or eliminate a vast array of serious and prevalent health conditions, ranging from senility to cancer. [See “Other Benefits of EDTA Chelation” below.]

Are there any significant risks with chelation? When administered by a properly trained physician, according to Dr. Gordon, IV EDTA has an extremely low risk of side effects—less than 1 in 10,000 patients. And mortality rates for chelation, when carried out according to accepted protocols, approaches 0 percent.{ref19}

How to use Oral EDTA to protect your arteries, heart, and more

Somewhat less well known, among consumers and healthcare professionals, are the benefits of the oral form EDTA Chelation therapy—in which the same EDTA compound used intravenously is taken orally, in doses high enough to be effective, yet safe enough to be taken without a doctor’s intervention.

“It is my firm belief,” says Dr. Gordon, “that anyone considering using aspirin for the prevention of heart attack should learn everything they can about oral EDTA. It is my belief that EDTA is as much as 300 times safer than aspirin.”

Oral chelation supplements keep your arteries plaque-free

As with the early IV chelation studies, the early clinical studies with oral EDTA were also promising, including loss of fat in rats, reduction of cholesterol in rabbits, and reduced blood pressure in humans. Consequently, a study of the effects of oral EDTA on patients with atherosclerosis and/or hypertension was conducted on 10 patients. Four of these patients had hypertension, four had angina pectoris, one had peripheral vascular disease (intermittent claudication), and one was recovering from a heart attack. All were treated with 1 gram of oral EDTA daily for 3 months.

The oral supplements caused a significant drop in the patients’ blood pressure … cholesterol … leg pain … and chest pain

Seven of the ten patients experienced significant reductions in their cholesterol levels, and blood pressure was reduced in all ten. The most marked change occurred in the patient with intermittent claudication, whose cholesterol dropped from 278 mg per 100 ml to 128! This patient also reported improved exercise tolerance, and the researchers found improved pulsations in the extremities. The four patients with angina pectoris also all reported improvement.{ref20}

In another series of 20 patients who suffered from high cholesterol, hypertension, angina or peripheral vascular disease, one gram of EDTA was administered orally every day for 3 months. During that short time, elevated cholesterol levels in nine of the patients dropped to within the normal range. No adverse results were experienced by any of the patients. Angina attacks were reduced in frequency and severity in five individuals. One person, who previously had suffered a heart attack and experienced several angina attacks daily thereafter, obtained complete relief.{ref21}

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In another study, two patients with extremely elevated cholesterol were treated with oral EDTA. One patient took EDTA in progressively increasing doses ranging from 500 mg to 4 gm daily for one year, and the other took 1,000 mg daily for three years. Although the first patient suffered a heart attack after three years of therapy, she recovered uneventfully and had reduced angina pains and improved sense of well-being with continued use of EDTA. The second patient—in addition to high cholesterol—had a condition known as xanthomatosis (yellowish papules in the skin, related to elevated blood lipids). She not only experienced dramatic reductions in her cholesterol levels with oral EDTA treatment, but her skin lesions completely resolved.{ref23}

In short, you can use oral chelation supplements to …

  • Cleanse your system of heavy metal toxicity and harmful calcium deposits in the arteries
  • Help thin the blood and prevent the formation of blood clots—and reduce your risk of heart attack or stroke
  • Lower your blood pressure and cholesterol levels (One of Dr. Gordon’s patients at Stanford University could not get her cholesterol below 500. Using ETDA-based chelation-based formula, her cholesterol lowered to 200—a remarkable result.)
  • Neutralize free-radicals … a major cause of atherosclerosis, as well as accelerated aging, cancer, and arthritis

Who should use oral chelation?

Oral EDTA is not meant to replace IV therapy for those people who have serious vascular disease. It is very useful, though, for people who have completed an IV course and want to stay on a maintenance program … for people who “for whatever reason” wish to avoid IV chelation … and for those whose IV treatments may have been interrupted.

Oral chelation is a safe, powerful disease fighter. It works. And considering that vascular diseases and blockages occur throughout the entire body, chelation is an ideal preventative and treatment. {pagebreak}

How much to take … how to know it’s working … and how to further enhance the benefits

The dose of oral EDTA used in the studies cited above ranges from a low of 500 milligrams per day to a high of 4,000 milligrams per day, with the most common dose being around 1,000 to 2,000 milligrams. Unfortunately, the majority of oral chelation supplements available today make it nearly impossible for you to consume the recommended amount, without inordinate hassle … and stomachache. With some chelation supplements, you need to take up to 40 capsules per day to get the high-level dose of 4,000 milligrams of EDTA per day! {ads}

In addition, recent research has shown that, aside from EDTA, there are two natural compounds that also function as excellent chelation agents: garlic and malic acid.

Some oral chelation supplements do include garlic … but again, you have to take so much of the supplement that, needless to say, your daily dose of the garlic can become a bit on the high side, and a bit unpleasant. Of all the chelation formulations available today, only one provides enough EDTA per capsule—250 milligrams, or 0.25 grams—to maintain the recommended daily dose conveniently, and at minimum cost and hassle. This high-quality product, called CardioClear®, is quite simply the most effective and convenient oral chelation supplement you can find. In addition to providing the optimum dose of EDTA, malic acid, and garlic, CardioClear also includes parsley extract to absorb the garlic odor.

If you have a known CVD condition … you should see a qualified doctor and ask about IV chelation and oral chelation. If you have a condition but it is not serious enough to require medical attention now, then oral chelation alone is a good choice for maintenance and prevention. Finally, if you do not have a known condition, then CardioClear—the most powerful and reliable way to heal your arteries and support your entire circulatory system—can help keep you protected for life. SP

Other Benefits of EDTA Chelation*

  • Prevents cholesterol deposits
  • Heals calcified necrotic ulcers
  • Reduces blood cholesterol levels
  • Reduces intermittent claudication
  • Lowers high blood pressure
  • Improves vision in diabetic retinopathy
  • Avoids by-pass surgery
  • Decreases macular degeneration
  • Avoids angioplasty
  • Dissolves small cataracts
  • Reserves digitalis toxicity
  • Eliminates heavy metal toxicity
  • Removes calcium from atherosclerotic plaques
  • Makes arterial walls more flexible
  • Dissolves intra-arterial blood clots
  • Prevents osteoarthritis
  • Normalizes cardiac arrhythmias
  • Reduces rheumatoid arthritis symptoms
  • Has an anti-aging effect
  • Lowers diabetics’ insulin needs
  • Reduces excessive heart contractions
  • Reduces Alzheimer-like symptoms
  • Increases intracellular potassium
  • Reverses senility
  • Reduces heart irritability
  • Reduces stroke/heart attack after-effects
  • Improves heart function
  • Prevents cancer
  • Removes mineral and drug deposits
  • Improves memory
  • Dissolves kidney stones
  • Reverses diabetic gangrene
  • Reduces serum iron levels
  • Restores impaired vision
  • Reduces heart valve calcification
  • Reduces varicose veins

*Adapted from Walker M., Gordon G., Douglass W.C.: The Chelation Answer

To find a doctor qualified …

to provide you with IV chelation treatments, contact the American College for Advancement in Medicine (ACAM) at:

ACAM
23121 Verdugo Dr., Ste. 204
Laguna Hills, CA 92653
800 532 3688
http://www.acam.org

EDTA Chelation therapy appears to be extremely safe, but as with almost any drug or supplement, there are potential adverse effects of EDTA chelation. One danger is nephrotoxicity (kidney damage). This is dependent on the dose, the rate of infusion, the patient’s kidney function, and the patient’s body burden of toxic heavy metals. Kidney damage was not uncommon in the early days of chelation therapy, when doses of EDTA in the range of 5-10 grams per day were used, and treatments were administered as often as 5 days per week.

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Kidney damage can be easily prevented, however, by carefully adjusting the frequency, dose, and rate in which the EDTA is administered. In addition, judicious administration of EDTA over prolonged periods (three to six months and longer) actually improved kidney function.

Other potential adverse effects include hypocalcemia (excessively low blood levels of calcium) due to EDTA’s binding excessively with calcium in the blood, hypoglycemia (low blood sugar), believed to be due to accompanying hypocalcemia, and phlebitis (inflammation of the vein), usually due to improperly prepared solutions. Rarely reported side effects include chills and fever following infusion, exacerbation of congestive heart failure due to fluid overload, fatigue (usually due to hypoglycemia or hypocalcemia), seizures, arrhythmias, or rash. The risk of incurring any of the above adverse effects has further been greatly reduced by the recent finding of Drs. Grant Born and Tammy Geurkink{ref23} that even greater benefit can be obtained by most patients who are treated with only 1.5 grams of EDTA per treatment, rather than with the standard dose of three grams. (But this refers to the IV infusion of EDTA, not to be confused with dosages for oral use, which are in the range of 500 mg to 4,000 mg per day.)

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References

  1. EDTA Chelation: A Misunderstood Therapy for Atherosclerosis and Other Diseases, by Ward Dean, MD, August 1997, VRP Library, http://www.vrp.com.
  2. EDTA Chelation: A Misunderstood Therapy for Atherosclerosis and Other Diseases, by Ward Dean, MD, August 1997, VRP Library, http://www.vrp.com.
  3. Parisi AF, Folland ED, Hartigan PA. Comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. N Engl J Med 1992;326:10-16.Abstract 
  4. Edmunds LH, Stephenson LW, Edie RN, Ratcliffe MB. Open-heart surgery in octogenarians. N Engl J Med 1988; 319:131-136.Abstract 
  5. CASS Principal Investigators and the Associates. Coronary artery surgery study (CASS): a randomized trial of coronary artery bypass surgery: Survival data. Circulation. 1983; 68: 939-950.Abstract 
  6. Arom KV, Cohen DE, Strobl FT. Effect of intraoperative intervention on neurological outcome based on electroencephalographic monitoring during cardiopulmonary bypass.Ann Thorac Surg. 1988; 48:476-483.Abstract 
  7. Arom KV, Cohen DE, Strobl FT. Effect of intraoperative intervention on neurological outcome based on electroencephalographic monitoring during cardiopulmonary bypass.Ann Thorac Surg. 1988; 48:476-483.Abstract 
  8. Center for Disease control website: http://www.cdc.gov
  9. Cranton, Elmer. Bypassing Bypass (2d Ed). Medex Publishers, Trout Dale, VA 24378-0044, 1992.
  10. EDTA Chelation: A Misunderstood Therapy for Atherosclerosis and Other Diseases, by Ward Dean, MD, August 1997, VRP Library.http://www.vrp.com.
  11. Harman, D. The biologic clock: The mitochondria? J Am Geriatr Soc, 1972, 20: 145-147.
  12. EDTA Chelation: A Misunderstood Therapy for Atherosclerosis and Other Diseases, by Ward Dean, MD, August 1997, VRP Library,http://www.vrp.com.
  13. Clarke NE, Clarke CN, Mosher RE. Treatment of angina pectoris with disodium ethelyne diamene tetraacetic acid. Am J Med Sci. 1956: December: 654-666.Abstract 
  14. Meltzer LE, Ural E, Kitchell JR. The treatment of coronary artery heart disease with disodium EDTA. In: Seven M, ed. Metal-Binding in Medicine, Philadelphia: JB Lippincott: 1960.Abstract 
  15. These papers, The correlation between EDTA Chelation Therapy and improvement in cardiovascular function: A Meta-Analysis, and EDTA Chelation Treatment for vascular disease: A Meta-Analysis using unpublished data, both by L.T. Chappell and J.P. Stahl, were published in the Journal of Advancement in Medicine in 1993 and 1994.
  16. Hancke, C. and Flytlie, K, Benefits of EDTA Chelation Therapy in Arteriosclerosis: A retrospective study of 470 patients, Journal of Advancement in Medicine, 1993, 6:3, 161-171.
  17. Olszewer E, Carter JP. EDTA chelation therapy in chronic degenerative disease. Med Hypotheses. 1988; 27:41-49.Abstract 
  18. Olszewer E, Sabbag FC, Carter JP. A pilot double-blind study of sodium-magnesium EDTA in peripheral vascular disease. J Natl Med Assoc 1990; 82:173-174.Abstract 
  19. Hancke C, Flytie K. Benefits of EDTA chelation therapy on arteriosclerosis. J Adv Med. 1993; 6:161-172.
  20. Chappell LT, Janson M. EDTA chelation therapy in the treatment of vascular disease. J Cardiovasc Nurs. 1996; 10:78-86.Abstract 
  21. Perry, H. Mitchell, Schroeder, Henry A. Depression of cholesterol levels in human plasma following ethylenediamine tetracetate and hydralazine. J Chronic Diseases, 1955, 2: 5, 520-532.Abstract 
  22. Schroeder, Henry A. A practical method for the reduction of plasma cholesterol in man. J Chronic Diseases, 1956, 4: 461-468.Abstract 
  23. Perry, Jr., and Camel, G., Some effects of CaNa2EDTA on plasma cholesterol and urinary zinc in man, in: Metal Binding in Medicine, by Marvin J. Seven and L. Audrey Johnson (eds), 1960, J.B. Lippincott Company, Philadelphia, 209-215.
  24. Born, G.R., and Geurkink, T.L. Improved peripheral vascular function with low dose intravenous ethylene diamine tetraacetic acid (EDTA). Townsend Letter for Doctors. July, 1994, # 132, 722-726.